The best Side of pkrrating
3B). R526 in the loop in between αJ and αI anchors check here the C-terminal part of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the primary chain carbonyl of R413. The suggestion on the activation phase is stabilized by a hydrogen bond in between Y454 and E480